Research Director, Biologist

Dr Kalliopi Manola is Research Director with expertise in cytogenetic and molecular investigation of genetic diseases and hematological malignancies. Her scientific interests include genetic and epigenetic investigation of leukemogenesis and investigation of genetic predisposition of multifactorial diseases. She holds BSc in Biology (1993) and PhD from Medical School of Kapodistrian University of Athens (2003). She has been trained in molecular biology techniques in the Laboratory of Molecular Biology of the University of Wales (1993) and in molecular techniques of hematological malignancies in the Department of Medical & Molecular Genetics, King’s College, London, UK (2014).

She is the Representative Cytogeneticist of Greece in the European Working Group (EWOG- MDS/JMML/SAA) of Myelodysplastic Syndrome (MDS), Juvenile Myelomonocytic Leukemia (JMML) and Severe Aplastic Anemia (SAA) in Childhood as well as the Representative Cytogeneticist of Greece in the European study group of Acute Myeloid Leukemia in the framework of the European polycentric clinical study AIEOP-AML-BFM 2020.

She is responsible for karyotypic and molecular cytogenetic evaluation of bone marrow samples from patients with hematological malignancies and peripheral blood samples from people with genetic syndromes and infertile couples. She is official member of the European LeukemiaNet (Network of Excellence) and a scientific member of many international and Greek scientific societies such as European Cytogeneticists Association (ECA), European Hematology Association (EHA) and European Society of Human Genetics (ESHG). She has contributed to funding by participating in health services provided by the laboratory for more than 20 years and in funded research programs.

She has 45 publications in international peer-reviewed journals, 2 monographs (review articles) and 149 peer-reviewed presentations in International and National Conferences. She is reviewer in ≥15 international journals and funded programs. She has collaborations with foreign and Greek universities, research centers and hospitals. She is also responsible for supervising and guiding many doctoral dissertations and postgraduate and undergraduate theses at NCSR “Demokritos”.

Selected Publications

Selected Grants

Radiation Biodosimetry and Leukemia Cytogenetics

1998-2022 | Provision of services

Principal Investigator: Dr C. Sambani, NCSR “Demokritos”


Identification of genetic biomarkers associated with endometriosis-related infertility and malignant transformation

2018-2020 | Stavros Niarchos Foundation Programme for Industrial Fellowships

Endometriosis is one of the most common gynecological diseases and its prevalence increases to 50% in infertile women. Laparoscopy is the primary surgical choice for the diagnosis and treatment of endometriosis. The main aim of the proposed study is the identification of microRNA biomarkers for non-...


Molecular typing of triple negative breast cancer

2013-2015 | NSRF project - Program Thales

Principal Investigator: Dr George Fountzilas, Aristotle University of Thessaloniki


Breast cancer stem cells resistance mechanisms in genotoxic insults: Applications in diagnosis, personalized treatment strategies and prognosis of disease progression

2013-2015 | NSRF project - Program Thales

Principal Investigator: Dr Vlachodimitropoulos Dimitrios, National & Kapodistrian University of Athens


Strengthen and develop scientific and technological excellence in research and therapy of leukemia (CML, AML, ALL, CLL, MDS, CMPD) by integration of the leading national leukemia networks and their interdisciplinary partner groups in Europe

2004-2012 | EU FP6

The European LeukemiaNet is funded by the European Community, 6th Framework Programme

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