The LIFE RESYSTAL project’s main objective is to increase climate adaptation capacities and resilience of the European Health Infrastructure (EHI) and systems and related dependant critical infrastructures. To achieve this, the project will a) set the basis of a European Network for the climate adaptation of the European health sector; b) provide science based support for implementing Climate Change Adaptation measures applicable to any EHI; and c) demonstrate EHI adaptation in diverse climate conditions and facilitate and promote EHI resilience.