Education Activities

Education activities per Research Area

INRASTES has long reputation and strong commitment in postgraduate education and training, since the establishment of NCSR “Demokritos” in the 1960’s. Our research groups are involved in various education activities, including the supervision of graduate students, PhD candidates and junior postdocs, and running across the four different research pillars of the institute. In certain cases, postgraduate research projects can cover multiple pillars or be in collaboration with other institutes of “Demokritos”. A list of on-going and recently completed projects can be found below.

If you are interested in conducting your theses or training with us, please visit the corresponding sections:


Postgraduate and undergraduate teaching activities

Many of our researchers are invited lecturers in accredited postgraduate programmes organized by Universities in Greece and abroad, the Greek Atomic Energy Commission, and the International Atomic Energy Agency (IAEA). Delivered courses range from Radiation Physics, Nuclear Reactor Safety, Nuclear Analytical Techniques, Industrial Safety, Environment and Solar Energy, to Radiopharmaceuticals, Clinical Chemistry, Molecular Diagnostics and Protein Chemistry.


Dissemination actions

Our research and education activities are disseminated to final year Science and Engineering students and graduates during the annual Summer School of NCSR “Demokritos”, in the form of lectures, laboratory demonstrations and tours.
In addition, we participate in the regular visits organized by the Education office of NCSR “Demokritos”, where we welcome several hundred high-school students visiting our laboratories per year. We also deliver lectures and conduct demonstrations addressed to the general public, e.g. during the annual festivities organized under the European Researchers Nights.


Video presentation of INRASTES education activities (in Greek):


INRASTES Education Officers


List of on-going and recently completed theses

Theses list

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Papassava Afroditi

Novel target-specific radiopharmaceuticals

With the main goal of early diagnosis of various cancers, Radiopharmaceutical Science is directly linked to the best possible prognosis and the therapeutic approach that will be chosen afterwards.

The objective of this dissertation is the synthesis, characterization, and comparative evaluation of multimodal 99mTc and 68Ga imaging complexes, which carry as a pharmacophore moiety mannosylated dextrans of different molecular weight.

The radiolabeled mannosylated dextrans have been extensively studied for use in sentinel lymph node detection (SLND) and cancer diagnosis, and consist of a dextran backbone, several mannose moieties for the recognition from mannose receptors in sentinel lymph node macrophages as well as a chelating agent, necessary for binding to the radioactive metal.

The sentinel lymph node theory assumes that the first lymph node to receive lymph and metastatic cells from the primary site of the tumor is also the first site of the lymphogenic spread of the disease, that there are no skip metastases and that the absence of metastatic disease in the sentinel lymph node implies the absence of metastases in the entire lymphatic pathway. Thus, with the administration of these complexes, it is possible to in vivo visualize and localize the sentinel lymph node in a non-invasive manner.

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Makrypidi Konstantina

Radiolabelled tyrosine kinase inhibitors for the development of molecules of pharmacological interest

Objective of the project is the development of radiolabeled tyrosine kinase inhibitors that could be potentially used as radiopharmaceutical drugs for epidermal growth factor receptor family (Erb B) and specifically EGFR.

EGFR is overexpressed in a variety of tumors and involved in several signaling pathways regulating various cellular functions associated with carcinogenesis, metastasis, uncontrollable cell proliferation and resistance to some therapeutic methods. The EGFR inhibitors’ radiolabeling is among interesting issues of Radiopharmaceutical Chemistry, contributing to a valid diagnosis of tumors overexpressing EGFR and its metastases, used to monitor the patient’s response to the proposed treatment and to determine the appropriate treatment.

Following this perspective, the dissertation aims to develop radiolabeled EGFR inhibitors with radioisotopes used in Νuclear Μedicine for diagnosis and treatment. The inhibitors are either analogues of 4-anilinoquinazoline core or other structures used in Pharmaceutical Chemistry. The new analogues are evaluated as potential radiopharmaceuticals by in vitro studies, stability and lipophilicity studies as well as in vivo pharmacokinetic and / or imaging studies on experimental animals.

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